42-637 Nano-Bio-Photonics
12 units, Carnegie Mellon University
Light can penetrate biological tissues noninvasively. Most of the available biooptic tools are bulky. With the advent of novel nanotechnologies, building onchip integrated photonic devices for applications such as sensing, imaging, neural stimulation, and monitoring is now a possibility. These devices can be embedded in portable electronic devices such as cell phones for point of care diagnostics. This course is designed to convey the concepts of nanobiophotonics in a practical way to prepare students to engage in emerging photonic technologies. The course starts with a review of electrodynamics of lightwaves. The appropriate choice of wavelength and material platform is the next topic. Then optical waveguides and resonators are discussed. Resonancebased sensing is introduced followed by a discussion of the Figure of Merits FOMs used to design onchip sensors. Silicon photonics is introduced as an example of a CMOScompatible platform. Onchip spectroscopy is the next topic. The second part covers nanoplasmonics for biodetection and therapy. The design methods are discussed, followed by an overview of nanofabrication and chemical synthesis, and then a discussion of applications. The last part of this course will be dedicated to a review of recent applications such as Optogenetic neural stimulation, Calcium imaging, Cancer Imaging and Therapy. Senior or graduate standing required. This course is crosslisted with 18416. Although students in 18616 and 18416 will share the same lectures and recitations, students in 18616 will receive distinct course projects. Students in 18416 and 18616 will be graded on separate curves.
Prerequisites: none listed
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