09-705 Chemosensors and Biosensors
12 units, Carnegie Mellon University
Chemosensors and biosensors rely on recognition and signaling elements to transduce a molecularscale binding event into an observable signal. Students in this course will be introduced to current research and technology for detecting chemical and biological analytes in a variety of contexts, including environmental testing, biological probing and medical diagnostics. Recognition elements ranging from small organic molecules to antibodies will be presented, while various detection modes, including fluorescence, gravimetric and colorimetric, that illustrate different signaling elements will be discussed and compared. Issues to be addressed include sensitivity, selectivity and efficiency. Each sensor will be analyzed in terms of the physical chemistry, organic chemistry andor biochemistry underlying its function. This is a graduate level course that may also be appropriate for upper level undergraduates in chemistry and the biological sciences. The material in 0951809519 or 0971809719 would be appropriate background material for this course. 3 hrs. lec.
Prerequisites: (03-232 or 03-231 or 03-121) and (09-218 or 09-220)
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