03-738 Synthetic Biology

6 units, Carnegie Mellon University

This course discusses the design of artificial biological parts or systems for research, engineering and medical applications. The course is divided into two parts topdown and bottomup synthetic biology. In topdown synthetic biology, engineering of cells with new functions or new products with metabolic and genetic engineering techniques such as circuit building, directed evolution, CRISPRCas9 will be covered. In bottomup synthetic biology, the assembly of molecules to obtain a specific biological output such as in vitro reconstitution of cellular machinery, cell free protein expression system and construction of artificial cells will be discussed.

Prerequisites: 03-232 or 03-231

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